5FXV
Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HISTONE DEMETHYLASE UTY | polymer | 478 | 55006.4 | 2 | UniProt (O14607) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) | HOMO SAPIENS (HUMAN) | UBIQUITOUSLY-TRANSCRIBED TPR PROTEIN ON THE Y CHROMOSOME, UBIQUITOUSLY-TRANSCRIBED Y CHROMOSOME TETRATRICOPEPTIDE REPEAT PROTEIN |
| 2 | C, L (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, M (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 4 | E, N (A, B) | 4-CARBOXYPIPERIDINE | non-polymer | 129.2 | 2 | Chemie (MN1) | |||
| 5 | F, G, H, I, J... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 6 | S, T (A, B) | water | water | 18.0 | 769 | Chemie (HOH) |
Sequence modifications
A, B: 878 - 1347 (UniProt: O14607)
| PDB | External Database | Details |
|---|---|---|
| Met 877 | - | expression tag |
| Ala 1348 | - | expression tag |
| Glu 1349 | - | expression tag |
| Asn 1350 | - | expression tag |
| Leu 1351 | - | expression tag |
| Tyr 1352 | - | expression tag |
| Phe 1353 | - | expression tag |
| Gln 1354 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110012.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1119.7 | |
| All* | Total formula weight | 111132.5 |






