5FXR
IGFR-1R complex with a pyrimidine inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | polymer | 308 | 35178.3 | 1 | UniProt (P08069) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | INSULIN-LIKE GROWTH FACTOR I RECEPTOR, IGF-I RECEPTOR, IGFR-1R |
| 2 | B (A) | 5-chloranyl-4-imidazo[1,2-a]pyridin-3-yl-N-(3-methyl-1-piperidin-4-yl-pyrazol-4-yl)pyrimidin-2-amine | non-polymer | 408.9 | 1 | Chemie (8LN) | |||
| 3 | C (A) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A: 980 - 1286 (UniProt: P08069)
| PDB | External Database | Details |
|---|---|---|
| Gly 979 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35178.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 408.9 | |
| All* | Total formula weight | 35587.2 |
