5FXJ

GluN1b-GluN2B NMDA receptor structure-Class X

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1	polymer	846	95220.7	2	UniProt (P35439) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	RATTUS NORVEGICUS (NORWAY RAT)	GLUN1, GLUTAMATE NMDA RECEPTOR SUBUNIT ZETA-1, N-METHYL-D-A SPARTATE RECEPTOR SUBUNIT NR1, NMD-R1, GLUN1
2	B, D (B, D)	GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B	polymer	827	92931.1	2	UniProt (Q00960) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	RATTUS NORVEGICUS (NORWAY RAT)	GLUN2B, GLUTAMATE NMDA RECEPTOR SUBUNIT EPSILON-2, N-METHYL D-ASPARTATE RECEPTOR SUBTYPE 2B, NMDAR2B, NR2B, GLUN2B

Sequence modifications

A, C: 23 - 868 (UniProt: P35439)

PDB	External Database	Details
Gln 61	Asn 61	engineered mutation
Asp 260	Asn 239	engineered mutation
Gln 371	Asn 350	engineered mutation
Gln 492	Asn 471	engineered mutation
Gln 512	Asn 491	engineered mutation
Gln 615	Glu 594	engineered mutation
Ser 616	Glu 595	engineered mutation
Ser 618	Glu 597	engineered mutation
Thr 619	Glu 598	engineered mutation
Gln 792	Asn 771	engineered mutation
Cys 831	Phe 810	engineered mutation
Asn 865	Arg 844	engineered mutation
Gly 866	Arg 845	engineered mutation
Ala 867	Lys 846	engineered mutation

B, D: 27 - 852 (UniProt: Q00960)

PDB	External Database	Details
Gly 26	-	expression tag
Asp 348	Asn 348	engineered mutation
Cys 557	Asp 557	engineered mutation
Ser 588	Cys 588	engineered mutation
Ser 838	Cys 838	engineered mutation
Ser 849	Cys 849	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	376303.6
All*	Total formula weight	376303.6

*Water molecules are not included.