5FWW
Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 | polymer | 619 | 70093.9 | 1 | UniProt (O75581) Pfam (PF00058) Pfam (PF14670) In PDB | HOMO SAPIENS (HUMAN) | LRP-6 |
| 2 | B | KREMEN PROTEIN 1 | polymer | 293 | 32728.5 | 1 | UniProt (Q96MU8) Pfam (PF00431) Pfam (PF00051) Pfam (PF01822) In PDB | HOMO SAPIENS (HUMAN) | DICKKOPF RECEPTOR, KRINGLE DOMAIN-CONTAINING TRANSMEMBRANE PROTEIN 1, KRINGLE-CONTAINING PROTEIN MARKING THE EYE AND THE NOSE |
| 3 | C | DICKKOPF-RELATED PROTEIN 1 | polymer | 85 | 9607.1 | 1 | UniProt (O94907) Pfam (PF21481) Pfam (PF21479) In PDB | HOMO SAPIENS (HUMAN) | HDKK-1, SK |
| 4 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A: 630 - 1246 (UniProt: O75581)
| PDB | External Database | Details |
|---|---|---|
| Ala 628 | - | expression tag |
| Asp 629 | - | expression tag |
| Ile 1062 | Val 1062 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112429.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 112469.6 |
