5FUQ
CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD(P)H DEHYDROGENASE [QUINONE] 1 | polymer | 274 | 30926.7 | 2 | UniProt (P15559) Pfam (PF02525) | HOMO SAPIENS (HUMAN) | AZOREDUCTASE, DT-DIAPHORASE, DTD, MENADIONE REDUCTASE, NADPH, QUINONE OXIDOREDUCTASE 1, PHYLLOQUINONE REDUCTASE, QUINONE REDUCTASE 1, QR1, NADPH DEHYDROGENASE QUINONE 1 |
| 2 | C, H (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, E, I (A, B) | BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE] | non-polymer | 336.3 | 3 | Chemie (DTC) | |||
| 4 | F, G, J, K (A, B) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 274 (UniProt: P15559)
| PDB | External Database | Details |
|---|---|---|
| Arg 80 | His 80 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61853.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2816.2 | |
| All* | Total formula weight | 64669.5 |
