5FTU

Tetrameric complex of Latrophilin 3, Unc5D and FLRT2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I (A, E, I)	NETRIN RECEPTOR UNC5D	polymer	139	15923.8	3	UniProt (F1LW30)	RATTUS NORVEGICUS (NORWAY RAT)
2	B, F, J (B, F, J)	LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2	polymer	339	38411.9	3	UniProt (Q8BLU0) Pfam (PF13855) Pfam (PF01463)	MUS MUSCULUS (HOUSE MOUSE)	FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2, FLRT2
3	C, D, G, H, K... (C, D, G, H, K...)	ADHESION G PROTEIN-COUPLED RECEPTOR L3	polymer	383	43908.0	6	UniProt (Q80TS3) Pfam (PF02140) Pfam (PF02191)	MUS MUSCULUS (HOUSE MOUSE)
4	AA, BA, CA, M, N... (I, J, K, A, B...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	9	Chemie (NAG)
5	DA, FA, P, R, W... (K, L, C, D, G...)	SODIUM ION	non-polymer		23.0	6	Chemie (NA)
6	EA, GA, Q, S, X... (K, L, C, D, G...)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)

Sequence modifications

A, E, I: 32 - 161 (UniProt: F1LW30)

PDB	External Database	Details
Gly 162	-	expression tag
Thr 163	-	expression tag
Lys 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag

B, F, J: 35 - 362 (UniProt: Q8BLU0)

PDB	External Database	Details
Thr 33	-	expression tag
Gly 34	-	expression tag
Arg 363	-	expression tag
Thr 364	-	expression tag
Lys 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag

C, D, G, H, K, L: 92 - 463 (UniProt: Q80TS3)

PDB	External Database	Details
Thr 90	-	expression tag
Gly 91	-	expression tag
Gly 464	-	expression tag
Thr 465	-	expression tag
Lys 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	426455.3
Non-Polymers*	Number of molecules	21
	Total formula weight	2369.3
All*	Total formula weight	428824.6

*Water molecules are not included.