5FTQ
Crystal structure of the ALK kinase domain in complex with Cmpd 17
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ALK TYROSINE KINASE RECEPTOR | polymer | 315 | 35334.6 | 1 | UniProt (Q9UM73) Pfam (PF07714) In PDB | HOMO SAPIENS (HUMAN) | ANAPLASTIC LYMPHOMA KINASE, ALK |
| 2 | A | N-[5-(3,5-DIFLUOROBENZYL)-1H-INDAZOL-3-YL]-2-[(4-HYDROXYCYCLOHEXYL)AMINO]-4-(4-METHYLPIPERAZIN-1-YL) BENZAMIDE | non-polymer | 574.7 | 1 | Chemie (U4W) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A: 1094 - 1407 (UniProt: Q9UM73)
| PDB | External Database | Details |
|---|---|---|
| Gly 1093 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35334.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 666.8 | |
| All* | Total formula weight | 36001.4 |
