5FR9
Structure of transaminase ATA-117 arRmut11 from Arthrobacter sp. KNK168 inhibited with 1-(4-Bromophenyl)-2-fluoroethylamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | (R)-AMINE TRANSAMINASE | polymer | 333 | 36904.4 | 12 | UniProt (F7J696) Pfam (PF01063) | ARTHROBACTER SP. | TRANSAMINASE ATA-117 ARRMUT11 |
| 2 | M, N, O, P, Q... (A, B, C, D, E...) | [4-[3-(4-bromophenyl)-3-oxidanylidene-propyl]-6-methyl-5-oxidanyl-pyridin-3-yl]methyl phosphate | non-polymer | 428.2 | 12 | Chemie (9HC) | |||
| 3 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 297 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 330 (UniProt: F7J696)
| PDB | External Database | Details |
|---|---|---|
| Ala 331 | - | expression tag |
| Leu 332 | - | expression tag |
| Glu 333 | - | expression tag |
| Pro 8 | Ser 8 | engineered mutation |
| Phe 60 | Tyr 60 | engineered mutation |
| Tyr 61 | Leu 61 | engineered mutation |
| Thr 62 | His 62 | engineered mutation |
| Ala 65 | Val 65 | engineered mutation |
| Thr 69 | Val 69 | engineered mutation |
| Gly 81 | Asp 81 | engineered mutation |
| Ile 94 | Met 94 | engineered mutation |
| Leu 96 | Ile 96 | engineered mutation |
| Met 122 | Phe 122 | engineered mutation |
| Thr 124 | Ser 124 | engineered mutation |
| Thr 126 | Ser 126 | engineered mutation |
| Phe 136 | Gly 136 | engineered mutation |
| Ser 150 | Tyr 150 | engineered mutation |
| Cys 152 | Val 152 | engineered mutation |
| Leu 169 | Ala 169 | engineered mutation |
| Ile 199 | Val 199 | engineered mutation |
| Leu 209 | Ala 209 | engineered mutation |
| Cys 215 | Gly 215 | engineered mutation |
| Asn 217 | Gly 217 | engineered mutation |
| Pro 223 | Ser 223 | engineered mutation |
| Pro 269 | Leu 269 | engineered mutation |
| Tyr 273 | Leu 273 | engineered mutation |
| Ser 282 | Thr 282 | engineered mutation |
| Gly 284 | Ala 284 | engineered mutation |
| Ser 297 | Pro 297 | engineered mutation |
| Val 306 | Ile 306 | engineered mutation |
| Pro 321 | Ser 321 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 442852.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5138.1 | |
| All* | Total formula weight | 447990.8 |
