5FPV
Crystal structure of human JMJD2A in complex with compound KDOAM20A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | LYSINE-SPECIFIC DEMETHYLASE 4A | polymer | 360 | 41854.6 | 8 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | HOMO SAPIENS (HUMAN) | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A, JUMONJI DOMAIN-CONTAINING PROTEIN 2A |
| 2 | EA, HA, I, KA, O... (E, F, A, G, B...) | MANGANESE (II) ION | non-polymer | 54.9 | 8 | Chemie (MN) | |||
| 3 | FA, IA, J, LA, P... (E, F, A, G, B...) | 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid | non-polymer | 306.4 | 8 | Chemie (MMK) | |||
| 4 | AA, GA, JA, K, MA... (D, E, F, A, G...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 5 | BA, CA, DA, L, M... (D, A, G, B, H...) | NICKEL (II) ION | non-polymer | 58.7 | 15 | Chemie (NI) | |||
| 6 | AB, BB, CB, VA, WA... (F, G, H, A, B...) | water | water | 18.0 | 891 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 2 - 360 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 334836.9 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 4294.1 | |
| All* | Total formula weight | 339131.0 |
