5FPD

Structure of heat shock-related 70kDA protein 2 with small-molecule ligand pyrazine-2-carboxamide (AT513) in an alternate binding site.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	HEAT SHOCK-RELATED 70KDA PROTEIN 2	polymer	387	42383.0	2	UniProt (P54652) Pfam (PF00012)	HOMO SAPIENS (HUMAN)
2	C, D (A, B)	PYRAZINE-2-CARBOXAMIDE	non-polymer		123.1	2	Chemie (PZA)
3	E, F (A, B)	water	water		18.0	878	Chemie (HOH)

Sequence modifications

A, B: 0 - 385 (UniProt: P54652)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
-	Ser 2	deletion
-	Ala 3	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84766.0
Non-Polymers*	Number of molecules	2
	Total formula weight	246.2
All*	Total formula weight	85012.2

*Water molecules are not included.