5FPD
Structure of heat shock-related 70kDA protein 2 with small-molecule ligand pyrazine-2-carboxamide (AT513) in an alternate binding site.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | HEAT SHOCK-RELATED 70KDA PROTEIN 2 | polymer | 387 | 42383.0 | 2 | UniProt (P54652) Pfam (PF00012) In PDB | HOMO SAPIENS (HUMAN) | |
2 | A, B | PYRAZINE-2-CARBOXAMIDE | non-polymer | 123.1 | 2 | Chemie (PZA) | |||
3 | water | water | 18.0 | 878 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 385 (UniProt: P54652)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
- | Ser 2 | deletion |
- | Ala 3 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 84766.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 246.2 | |
All* | Total formula weight | 85012.2 |