5FOA

Crystal Structure of Human Complement C3b in complex with DAF (CCP2-4)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	COMPLEMENT C3 BETA CHAIN	polymer	645	71393.3	2	UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703)	HOMO SAPIENS (HUMAN)	C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PRO
2	B, D (B, D)	COMPLEMENT C3B ALPHA CHAIN	polymer	915	104074.1	2	UniProt (P01024) Pfam (PF07677) Pfam (PF01759) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) Pfam (PF21308)	HOMO SAPIENS (HUMAN)	C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PRO
3	E, F (E, F)	DECAY ACCELERATING FACTOR, CD55	polymer	194	21290.9	2	UniProt (P08174) Pfam (PF00084)	HOMO SAPIENS (HUMAN)	DECAY ACCELERATING FACTOR,

Sequence modifications

B, D: 749 - 1663 (UniProt: P01024)

PDB	External Database	Details
Glu 1013	Gln 1013	SEE REMARK 999

E, F: 97 - 285 (UniProt: P08174)

PDB	External Database	Details
Gly 95	-	expression tag
Ser 96	-	expression tag
Ala 286	-	expression tag
Ala 287	-	expression tag
Ala 288	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	393516.7
All*	Total formula weight	393516.7

*Water molecules are not included.