5FO8
Crystal Structure of Human Complement C3b in Complex with MCP (CCP1-4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | COMPLEMENT C3 | polymer | 645 | 71393.3 | 1 | UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) | HOMO SAPIENS (HUMAN) | C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 1, C3ADESARG, COMPLEMENT C3B |
| 2 | B (B) | COMPLEMENT C3 | polymer | 915 | 104074.1 | 1 | UniProt (P01024) Pfam (PF07677) Pfam (PF01759) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) Pfam (PF21308) | HOMO SAPIENS (HUMAN) | C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 1, C3ADESARG, COMPLEMENT C3B |
| 3 | C (C) | MEMBRANE COFACTOR PROTEIN | polymer | 252 | 28463.5 | 1 | UniProt (P15529) Pfam (PF00084) | HOMO SAPIENS (HUMAN) | TLX, TROPHOBLAST LEUKOCYTE COMMON ANTIGEN, MEMBRANE COFACTOR PROTEIN MCP, CD46 |
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | AA, BA, CA, DA, EA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 32 | Chemie (EDO) | |||
| 7 | LA, MA, NA (A, B, C) | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence modifications
B: 749 - 1663 (UniProt: P01024)
| PDB | External Database | Details |
|---|---|---|
| Glu 1013 | Gln 1013 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 203931.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 1986.2 | |
| All* | Total formula weight | 206928.1 |
