5FNU
Structure of the Keap1 Kelch domain in complex with a small molecule inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 | polymer | 304 | 33362.3 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) | MUS MUSCULUS (HOUSE MOUSE) | CYTOSOLIC INHIBITOR OF NRF2, INRF2, KEAP1 |
| 2 | B (A) | (3S)-3-(7-methoxy-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(((R)-4-methyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)phenyl)propanoic acid | non-polymer | 550.6 | 1 | Chemie (L6I) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence modifications
A: 322 - 624 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Gly 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33362.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 586.1 | |
| All* | Total formula weight | 33948.4 |
