5FNI
Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CARBONIC ANHYDRASE 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) | HOMO SAPIENS (HUMAN) | CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CAC, CARBONIC ANHYDRASE II, CA-II |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | E (A) | 5-[[3,4-bis(chloranyl)phenoxy]methyl]-1,2,4-triaza-3-azanidacyclopenta-1,4-diene | non-polymer | 244.1 | 1 | Chemie (YIH) | |||
| 6 | F (A) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29289.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 479.7 | |
| All* | Total formula weight | 29768.8 |
