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5FMH

Crystal structure of the E405K mutant of human apoptosis inducing factor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIALpolymer51055715.31UniProt (O95831)
Pfam (PF00070)
Pfam (PF14721)
HOMO SAPIENS (HUMAN)PROGRAMMED CELL DEATH PROTEIN 8, APOPTOSIS INDUCING FACTOR
2B
(A)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
3C
(A)
waterwater18.0334Chemie (HOH)
Sequence modifications
A: 104 - 613 (UniProt: O95831)
PDBExternal DatabaseDetails
Lys 405Glu 405engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight55715.3
Non-Polymers*Number of molecules1
Total formula weight785.5
All*Total formula weight56500.9
*Water molecules are not included.

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PDB entries from 2025-06-25

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