5FM3
Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | polymer | 355 | 40721.4 | 1 | UniProt (P07949) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | CADHERIN FAMILY MEMBER 12, PROTO-ONCOGENE C-RET |
| 2 | B (A) | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE | non-polymer | 281.4 | 1 | Chemie (PP1) | |||
| 3 | C (A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40721.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 281.4 | |
| All* | Total formula weight | 41002.8 |
