5FLX
Mammalian 40S HCV-IRES complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | 18S RRNA | polymer | 1869 | 602776.9 | 1 | GenBank (36162) | ORYCTOLAGUS CUNICULUS (RABBIT) | |
| 2 | B (A) | 40S RIBOSOMAL PROTEIN SA | polymer | 295 | 32883.9 | 1 | UniProt (P08865) Pfam (PF00318) Pfam (PF16122) | ORYCTOLAGUS CUNICULUS (RABBIT) | 37 KDA LAMININ RECEPTOR PRECURSOR, 37LRP, 37/67 KDA LAMININ RECEPTOR, LRP/LR, 67 KDA LAMININ RECEPTOR, 67LR, COLON CARCINOMA LAMININ-BINDING PROTEIN, LAMININ RECEPTOR 1,LAMR, LAMININ-BINDING PROTEIN PRECURSOR P40,LBP/P40,MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN MGR1-AG, NEM/1CHD4,40S RIBOSOMAL PROTEIN US2 |
| 3 | C (B) | 40S RIBOSOMAL PROTEIN S3A | polymer | 264 | 30002.1 | 1 | UniProt (P61247) Pfam (PF01015) | ORYCTOLAGUS CUNICULUS (RABBIT) | V-FOS TRANSFORMATION EFFECTOR PROTEIN, FTE-1,40S RIBOSOMAL PROTEIN ES1 |
| 4 | D (C) | 40S RIBOSOMAL PROTEIN S2 | polymer | 293 | 31376.5 | 1 | UniProt (P15880) Pfam (PF00333) Pfam (PF03719) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN S4,PROTEIN LLREP3,40S RIBOSOMAL PROTEIN US5 |
| 5 | E (D) | 40S RIBOSOMAL PROTEIN S3 | polymer | 243 | 26729.4 | 1 | UniProt (P23396) Pfam (PF07650) Pfam (PF00189) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US3 |
| 6 | F (E) | 40S RIBOSOMAL PROTEIN S4, Y ISOFORM 1 | polymer | 263 | 29512.8 | 1 | UniProt (P22090) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) Pfam (PF08071) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES4 |
| 7 | G (F) | 40S RIBOSOMAL PROTEIN S5 | polymer | 204 | 22913.5 | 1 | UniProt (P46782) Pfam (PF00177) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US7 |
| 8 | H (G) | 40S RIBOSOMAL PROTEIN S6 | polymer | 249 | 28751.9 | 1 | UniProt (P62753) Pfam (PF01092) | ORYCTOLAGUS CUNICULUS (RABBIT) | PHOSPHOPROTEIN NP33,40S RIBOSOMAL PROTEIN ES6 |
| 9 | I (H) | 40S RIBOSOMAL PROTEIN S7 | polymer | 194 | 22168.9 | 1 | UniProt (P62081) Pfam (PF01251) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES7 |
| 10 | J (I) | 40S RIBOSOMAL PROTEIN S8 | polymer | 208 | 24263.4 | 1 | UniProt (P62241) Pfam (PF01201) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES8 |
| 11 | K (J) | 40S RIBOSOMAL PROTEIN S9 | polymer | 194 | 22641.6 | 1 | UniProt (P46781) Pfam (PF00163) Pfam (PF01479) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US4 |
| 12 | L (K) | 40S RIBOSOMAL PROTEIN S10 | polymer | 165 | 18933.8 | 1 | UniProt (P46783) Pfam (PF03501) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES10 |
| 13 | M (L) | 40S RIBOSOMAL PROTEIN S11 | polymer | 158 | 18468.8 | 1 | UniProt (P62280) Pfam (PF16205) Pfam (PF00366) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US17 |
| 14 | N (M) | 40S RIBOSOMAL PROTEIN S12 | polymer | 132 | 14539.0 | 1 | UniProt (P25398) Pfam (PF01248) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES12 |
| 15 | O (N) | 40S RIBOSOMAL PROTEIN S13 | polymer | 151 | 17259.4 | 1 | UniProt (P62277) Pfam (PF08069) Pfam (PF00312) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US15 |
| 16 | P (O) | 40S RIBOSOMAL PROTEIN S14 | polymer | 151 | 16302.8 | 1 | UniProt (P62263) Pfam (PF00411) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US11 |
| 17 | Q (P) | 40S RIBOSOMAL PROTEIN S15 | polymer | 145 | 17076.2 | 1 | UniProt (P62841) Pfam (PF00203) | ORYCTOLAGUS CUNICULUS (RABBIT) | RIG PROTEIN, 40S RIBOSOMAL PROTEIN US19 |
| 18 | R (Q) | 40S RIBOSOMAL PROTEIN S16 | polymer | 146 | 16477.4 | 1 | UniProt (P62249) Pfam (PF00380) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US9 |
| 19 | S (R) | 40S RIBOSOMAL PROTEIN S17 | polymer | 135 | 15578.2 | 1 | UniProt (P08708) Pfam (PF00833) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES17 |
| 20 | T (S) | 40S RIBOSOMAL PROTEIN S18 | polymer | 152 | 17759.8 | 1 | UniProt (P62269) Pfam (PF00416) | ORYCTOLAGUS CUNICULUS (RABBIT) | KE-3,KE3,40S RIBOSOMAL PROTEIN US13 |
| 21 | U (T) | 40S RIBOSOMAL PROTEIN S19 | polymer | 145 | 16091.6 | 1 | UniProt (P39019) Pfam (PF01090) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES19 |
| 22 | V (U) | 40S RIBOSOMAL PROTEIN S20 | polymer | 119 | 13398.8 | 1 | UniProt (P60866) Pfam (PF00338) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US10 |
| 23 | W (V) | 40S RIBOSOMAL PROTEIN S21 | polymer | 83 | 9124.4 | 1 | UniProt (P63220) Pfam (PF01249) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES21 |
| 24 | X (W) | 40S RIBOSOMAL PROTEIN S15A | polymer | 130 | 14865.6 | 1 | UniProt (P62244) Pfam (PF00410) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US8 |
| 25 | Y (X) | 40S RIBOSOMAL PROTEIN S23 | polymer | 143 | 15844.7 | 1 | UniProt (P62266) Pfam (PF00164) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US12 |
| 26 | Z (Y) | 40S RIBOSOMAL PROTEIN S24 | polymer | 133 | 15463.3 | 1 | UniProt (P62847) Pfam (PF01282) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES24 |
| 27 | AA (Z) | 40S RIBOSOMAL PROTEIN S25 | polymer | 125 | 13776.2 | 1 | UniProt (P62851) Pfam (PF03297) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES25 |
| 28 | BA (a) | 40S RIBOSOMAL PROTEIN S26 | polymer | 115 | 13047.5 | 1 | UniProt (P62854) Pfam (PF01283) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES26 |
| 29 | CA (b) | 40S RIBOSOMAL PROTEIN S27 | polymer | 84 | 9480.2 | 1 | UniProt (P42677) Pfam (PF01667) | ORYCTOLAGUS CUNICULUS (RABBIT) | METALLOPAN-STIMULIN 1,MPS-1,40S RIBOSOMAL PROTEIN ES27 |
| 30 | DA (c) | 40S RIBOSOMAL PROTEIN S28 | polymer | 69 | 7855.1 | 1 | UniProt (P62857) Pfam (PF01200) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES28 |
| 31 | EA (d) | 40S RIBOSOMAL PROTEIN S29 | polymer | 56 | 6690.8 | 1 | UniProt (P62273) Pfam (PF00253) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN US14 |
| 32 | FA (e) | 40S RIBOSOMAL PROTEIN S30 | polymer | 59 | 6668.9 | 1 | UniProt (P62861) Pfam (PF04758) | ORYCTOLAGUS CUNICULUS (RABBIT) | 40S RIBOSOMAL PROTEIN ES30 |
| 33 | GA (f) | UBIQUITIN-40S RIBOSOMAL PROTEIN S27A | polymer | 156 | 18004.0 | 1 | UniProt (P62979) Pfam (PF00240) Pfam (PF01599) | ORYCTOLAGUS CUNICULUS (RABBIT) | UBIQUITIN CARBOXYL EXTENSION PROTEIN 80,40S RIBOSOMAL PROTEIN ES31 |
| 34 | HA (g) | GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-2-LIKE 1 | polymer | 317 | 35115.7 | 1 | UniProt (P63244) Pfam (PF00400) | ORYCTOLAGUS CUNICULUS (RABBIT) | CELL PROLIFERATION-INDUCING GENE 21 PROTEIN, GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 12.3,HUMAN LUNG CANCER ONCOGENE 7 PROTEIN, HLC-7,RECEPTOR FOR ACTIVATED C KINASE, RECEPTOR OF ACTIVATED PROTEIN KINASE C 1,RACK1,40S RIBOSOMAL PROTEIN RACK1 |
| 35 | IA (z) | HCV-IRES | polymer | 504 | 162190.1 | 1 | HEPATITIS C VIRUS (HCV) | ||
| 36 | AB, AC, AD, BB, BC... (1, D, X) | MAGNESIUM ION | non-polymer | 24.3 | 74 | Chemie (MG) | |||
| 37 | FD, GD (a, d) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 35 |
| Total formula weight | 1384032.9 | |
| Non-Polymers* | Number of molecules | 76 |
| Total formula weight | 1929.4 | |
| All* | Total formula weight | 1385962.2 |
