5FLM
Structure of transcribing mammalian RNA polymerase II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-DIRECTED RNA POLYMERASE | polymer | 1970 | 217436.1 | 1 | Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) UniProt (by SIFTS) (G3MZY8) | BOS TAURUS (BOVINE) | |
| 2 | B (B) | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 | polymer | 1174 | 134041.4 | 1 | UniProt (A5PJW8) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | BOS TAURUS (BOVINE) | DNA-DIRECTED RNA POLYMERASE II 140 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II SUBUNIT B, RNA POLYMERASE II SUBUNIT 2, RNA POLYMERASE II SUBUNIT B2 |
| 3 | C (C) | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 | polymer | 275 | 31466.1 | 1 | UniProt (Q3T0Q3) Pfam (PF01193) Pfam (PF01000) | BOS TAURUS (BOVINE) | RNA POLYMERASE II SUBUNIT B3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT C |
| 4 | D (D) | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 | polymer | 142 | 16347.3 | 1 | UniProt (Q1JQ91) Pfam (PF03874) | BOS TAURUS (BOVINE) | RNA POLYMERASE II SUBUNIT B4, DNA-DIRECTED RNA POLYMERASE II SUBUNIT D, RNA POLYMERASE II 16 KDA SUBUNIT, RPB16 |
| 5 | E (E) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 | polymer | 210 | 24514.2 | 1 | UniProt (Q2T9T3) Pfam (PF03871) Pfam (PF01191) | BOS TAURUS (BOVINE) | RNA POLYMERASES I, II, AND III SUBUNIT ABC1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT E, RPB5 HOMOLOG |
| 6 | F (F) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 | polymer | 127 | 14491.0 | 1 | Pfam (PF01192) UniProt (by SIFTS) (Q32PE0) | BOS TAURUS (BOVINE) | RNA POLYMERASES I, II, AND III SUBUNIT ABC2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT F, RPB6 HOMOLOG |
| 7 | G (G) | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (Q5E9B8) Pfam (PF03876) Pfam (PF00575) | BOS TAURUS (BOVINE) | RNA POLYMERASE II SUBUNIT B7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT G |
| 8 | H (H) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (F2Z4H3) Pfam (PF03870) | BOS TAURUS (BOVINE) | RNA POLYMERASES I, II, AND III SUBUNIT ABC3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT H, DNA-DIRECTED RNA POLYMERASES I, AND III 17.1 KDA POLYPEPTIDE, RPB17, RPB8 HOMOLOG, HRPB8 |
| 9 | I (I) | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 | polymer | 125 | 14507.2 | 1 | UniProt (Q32P73) Pfam (PF02150) Pfam (PF01096) | BOS TAURUS (BOVINE) | RNA POLYMERASE II SUBUNIT B9, DNA-DIRECTED RNA POLYMERASE II SUBUNIT I |
| 10 | J (J) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (Q32P78) Pfam (PF01194) | BOS TAURUS (BOVINE) | RNA POLYMERASES I, II, AND III SUBUNIT ABC5, DNA-DIRECTED RNA POLYMERASE III SUBUNIT L |
| 11 | K (K) | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 | polymer | 117 | 13310.3 | 1 | UniProt (Q32P79) Pfam (PF13656) | BOS TAURUS (BOVINE) | RNA POLYMERASE II SUBUNIT B11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT J |
| 12 | L (L) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 | polymer | 58 | 7018.2 | 1 | UniProt (Q3ZBC0) Pfam (PF03604) | BOS TAURUS (BOVINE) | RNA POLYMERASES I, II, AND III SUBUNIT ABC4, DNA-DIRECTED RNA POLYMERASE II SUBUNIT K |
| 13 | M (N) | DNA, DNA-RNA ELONGATION SCAFFOLD | polymer | 39 | 12085.8 | 1 | SYNTHETIC CONSTRUCT | ||
| 14 | N (P) | RNA, DNA-RNA ELONGATION SCAFFOLD | polymer | 20 | 6414.9 | 1 | SYNTHETIC CONSTRUCT | ||
| 15 | O (T) | DNA, DNA-RNA ELONGATION SCAFFOLD | polymer | 39 | 11942.7 | 1 | SYNTHETIC CONSTRUCT | ||
| 16 | P, Q, S, T, U... (A, B, C, I, J...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 17 | R (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 547706.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 548254.5 |
