5FHR
Crystal structure of Y200L mutant of Rat Catechol-O-Methyltransferase in complex with AdoMet and 3,5-dinitrocatechol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Catechol O-methyltransferase | polymer | 213 | 23931.5 | 2 | UniProt (P22734) Pfam (PF01596) | Rattus norvegicus (norway Rat) | |
| 2 | C, G (A, B) | 3,5-DINITROCATECHOL | non-polymer | 200.1 | 2 | Chemie (DNC) | |||
| 3 | D, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, I (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 5 | F (A) | BROMIDE ION | non-polymer | 79.9 | 1 | Chemie (BR) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 729 | Chemie (HOH) |
Sequence modifications
A, B: 46 - 258 (UniProt: P22734)
| PDB | External Database | Details |
|---|---|---|
| Leu 243 | Tyr 243 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47863.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1325.6 | |
| All* | Total formula weight | 49188.6 |
