5FHR
Crystal structure of Y200L mutant of Rat Catechol-O-Methyltransferase in complex with AdoMet and 3,5-dinitrocatechol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Catechol O-methyltransferase | polymer | 213 | 23931.5 | 2 | UniProt (P22734) Pfam (PF01596) | Rattus norvegicus (norway Rat) | |
| 2 | C, G (A, B) | 3,5-DINITROCATECHOL | non-polymer | 200.1 | 2 | Chemie (DNC) PubChem (3870203) | |||
| 3 | D, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | E, I (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (9865603) PubChem (145712080) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 5 | F (A) | BROMIDE ION | non-polymer | 79.9 | 1 | Chemie (BR) PubChem (259) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 729 | Chemie (HOH) |
Sequence modifications
A, B: 46 - 258 (UniProt: P22734)
| PDB | External Database | Details |
|---|---|---|
| Leu 243 | Tyr 243 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47863.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1325.6 | |
| All* | Total formula weight | 49188.6 |
