5FF1
Two way mode of binding of antithyroid drug methimazole to mammalian heme peroxidases: Structure of the complex of lactoperoxidase with methimazole at 1.97 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lactoperoxidase | polymer | 595 | 67529.8 | 2 | UniProt (A3F9D6) Pfam (PF03098) UniProt (by SIFTS) (A0A452E9Y6) | Capra hircus (Goat) | |
| 2 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, E, EA, U (A, B) | 1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE | non-polymer | 114.2 | 4 | Chemie (MMZ) | |||
| 4 | F, G, H, I, V... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 5 | J, Y (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 6 | K, Z (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | AA, BA, CA, DA, L... (B, A) | NITRATE ION | non-polymer | 62.0 | 9 | Chemie (NO3) | |||
| 8 | FA, GA, HA, IA, Q... (B, A) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 9 | JA, KA (A, B) | water | water | 18.0 | 775 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 135059.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 4613.1 | |
| All* | Total formula weight | 140097.0 |
