5FDL
Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with IDX899
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | P51 Reverse transcriptase | polymer | 557 | 64086.4 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus 1 (HIV-1) | Pr160Gag-Pol |
| 2 | B | P66 Reverse transcriptase | polymer | 440 | 51295.9 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | Human immunodeficiency virus type 1 (HIV-1) | Pr160Gag-Pol |
| 3 | A | methyl (R)-(2-carbamoyl-5-chloro-1H-indol-3-yl)[3-(2-cyanoethyl)-5-methylphenyl]phosphinate | non-polymer | 415.8 | 1 | Chemie (5DV) |
Sequence modifications
A: 1 - 557 (UniProt: P03366)
B: 1 - 440 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Lys 702 | engineered mutation |
| Cys 181 | Tyr 780 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Lys 702 | engineered mutation |
| Cys 181 | Tyr 780 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115382.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 415.8 | |
| All* | Total formula weight | 115798.2 |
