5FDI
Crystal structure of Human Carbonic Anhydrase II with the anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | 1,1-bis(oxidanylidene)-3-[(sulfamoylamino)methyl]-1-benzothiophene | non-polymer | 274.3 | 1 | Chemie (5WM) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | A | 4-(HYDROXYMERCURY)BENZOIC ACID | non-polymer | 338.7 | 1 | Chemie (HGB) | |||
| 6 | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29289.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 770.5 | |
| All* | Total formula weight | 30059.6 |
