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5FBK

Crystal structure of the extracellular domain of human calcium sensing receptor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BExtracellular calcium-sensing receptorpolymer56864215.42UniProt (P41180)
Pfam (PF01094)
In PDB
Homo sapiens (Human)CaSR,Parathyroid cell calcium-sensing receptor 1,PCaR1
2A, BCYCLOMETHYLTRYPTOPHANnon-polymer216.22Chemie (TCR)
3A, B2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.28Chemie (NAG)
4A, BCHLORIDE IONnon-polymer35.56Chemie (CL)
5A, BBICARBONATE IONnon-polymer61.02Chemie (BCT)
6A, BMAGNESIUM IONnon-polymer24.33Chemie (MG)
7waterwater18.0323Chemie (HOH)
Sequence modifications
A, B: 20 - 541 (UniProt: P41180)
PDBExternal DatabaseDetails
Met -26-initiating methionine
Arg -25-expression tag
Leu -24-expression tag
Leu -23-expression tag
Thr -22-expression tag
Ala -21-expression tag
Leu -20-expression tag
Phe -19-expression tag
Ala -18-expression tag
Tyr -17-expression tag
Phe -16-expression tag
Ile -15-expression tag
Val -14-expression tag
Ala -13-expression tag
Leu -12-expression tag
Ile -11-expression tag
Leu -10-expression tag
Ala -9-expression tag
Phe -8-expression tag
Ser -7-expression tag
Val -6-expression tag
Ser -5-expression tag
Ala -4-expression tag
Lys -3-expression tag
Ser -2-expression tag
Met -1-expression tag
His 0-expression tag
His 1-expression tag
His 2-expression tag
His 3-expression tag
His 4-expression tag
His 5-expression tag
His 6-expression tag
His 7-expression tag
Ser 8-expression tag
Ala 9-expression tag
Trp 10-expression tag
Ser 11-expression tag
His 12-expression tag
Pro 13-expression tag
Gln 14-expression tag
Phe 15-expression tag
Glu 16-expression tag
Lys 17-expression tag
Glu 18-expression tag
Phe 19-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight128430.8
Non-Polymers*Number of molecules21
Total formula weight2609.8
All*Total formula weight131040.6
*Water molecules are not included.

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數據於2024-09-18公開中

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