5FAZ
Crystal structure of the Q108K:K40L:T51V mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.4 Angstrom Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retinol-binding protein 2 | polymer | 133 | 15580.5 | 2 | UniProt (P50120) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinol-binding protein II,CRBP-II |
| 2 | C, E (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) PubChem (175) | |||
| 3 | D, F (A, B) | RETINAL | non-polymer | 284.4 | 2 | Chemie (RET) PubChem (1070) PubChem (23254473) PubChem (177675058) PubChem (638015) PubChem (87082476) PubChem (87110449) PubChem (87110609) PubChem (88398773) PubChem (88407543) PubChem (5280490) PubChem (5353924) PubChem (5381765) PubChem (6436079) PubChem (6436082) PubChem (11426127) PubChem (12227253) PubChem (12227254) PubChem (12227256) PubChem (12227257) PubChem (12227258) PubChem (12227259) PubChem (12227269) PubChem (12227270) PubChem (12227271) PubChem (134688327) PubChem (140510408) PubChem (145826762) PubChem (169423542) PubChem (172878320) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 133 (UniProt: P50120)
| PDB | External Database | Details |
|---|---|---|
| Leu 40 | Lys 41 | engineered mutation |
| Val 51 | Thr 52 | engineered mutation |
| Lys 108 | Gln 109 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31161.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 687.0 | |
| All* | Total formula weight | 31848.0 |
