5FAF
N184K pathological variant of gelsolin domain 2 (orthorhombic form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Gelsolin | polymer | 119 | 13181.7 | 1 | UniProt (P06396) Pfam (PF00626) | Homo sapiens (Human) | AGEL,Actin-depolymerizing factor,ADF,Brevin |
| 2 | B, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | C, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | J (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 151 - 266 (UniProt: P06396)
| PDB | External Database | Details |
|---|---|---|
| Gly 148 | - | expression tag |
| Ser 149 | - | expression tag |
| His 150 | - | expression tag |
| Lys 184 | Asn 211 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13181.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 486.4 | |
| All* | Total formula weight | 13668.1 |
