5FAF
N184K pathological variant of gelsolin domain 2 (orthorhombic form)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Gelsolin | polymer | 119 | 13181.7 | 1 | UniProt (P06396) Pfam (PF00626) In PDB | Homo sapiens (Human) | AGEL,Actin-depolymerizing factor,ADF,Brevin |
2 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
5 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
6 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 151 - 266 (UniProt: P06396)
PDB | External Database | Details |
---|---|---|
Gly 148 | - | expression tag |
Ser 149 | - | expression tag |
His 150 | - | expression tag |
Lys 184 | Asn 211 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13181.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 486.4 | |
All* | Total formula weight | 13668.1 |