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5F9W

Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, G)
clade A/E 93TH057 HIV-1 gp120 corepolymer35339211.42UniProt (A0A0M3KKW9)
Pfam (PF00516)
Human immunodeficiency virus 1
2B, E
(B, H)
Heavy chain of CH235-lineage antibody CH235polymer22524241.12Homo sapiens
3C, F
(C, L)
Light chain of CH235-lineage antibody CH235polymer21323407.12Homo sapiens
4AA, BA, CA, DA, EA...
(G, A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.227Chemie (NAG)
5JA, U, V
(H, A, B)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
6KA, LA, MA, NA, OA...
(A, B, C, G, H...)
waterwater18.074Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight173719.2
Non-Polymers*Number of molecules30
Total formula weight6257.5
All*Total formula weight179976.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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