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5F9O

Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.09 in complex with HIV-1 clade A/E 93TH057 gp120

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
clade A/E 93TH057 HIV-1 gp120 corepolymer35239082.31UniProt (A0A0M3KKW9)
Pfam (PF00516)
Human immunodeficiency virus 1
2B
(H)
CH235.9 Heavy chainpolymer23425218.61Homo sapiens
3C
(L)
CH235.09 Light chainpolymer21323532.21Homo sapiens
4D, E, F, G, H...
(G)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.212Chemie (NAG)
5P, Q
(G)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.32Chemie (EPE)
6R
(G)
POLYETHYLENE GLYCOL (N=34)non-polymer1529.81Chemie (15P)
7S, T, U
(G, H, L)
waterwater18.0460Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight87833.1
Non-Polymers*Number of molecules15
Total formula weight4660.9
All*Total formula weight92494.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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