5F96
Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.12 in complex with HIV-1 clade A/E 93TH057 gp120
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | clade A/E 93TH057 HIV-1 gp120 core | polymer | 353 | 39211.4 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (H) | HEAVY CHAIN OF ANTIBODY CH235.12 | polymer | 225 | 24319.4 | 1 | Homo sapiens | ||
| 3 | C (L) | LIGHT CHAIN OF ANTIBODY CH235.12 | polymer | 213 | 23451.0 | 1 | Homo sapiens | ||
| 4 | D, E, F, G, H... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 5 | P, Q, R (G, L) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 3 | Chemie (EPE) | |||
| 6 | S, T, U (G, H, L) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86981.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3369.4 | |
| All* | Total formula weight | 90351.2 |
