5F78

Crystal structure of Mutant N87T of adenosine/Methylthioadenosine phosphorylase from Schistosoma mansoni in APO form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Methylthioadenosine phosphorylase	polymer	320	35246.5	6	UniProt (I0B503) Pfam (PF01048)	Schistosoma mansoni (Blood fluke)
2	G, H, I, J, K... (A, B, C, D, E...)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
3	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	1853	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 299 (UniProt: I0B503)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Thr 87	Asn 87	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	211478.9
Non-Polymers*	Number of molecules	6
	Total formula weight	576.4
All*	Total formula weight	212055.3

*Water molecules are not included.