5F6X
Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 2 (mercaptobenzoxazole from cocktail screen)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | SUMO-conjugating enzyme UBC9 | polymer | 157 | 17725.4 | 1 | UniProt (P63279) Pfam (PF00179) In PDB | Homo sapiens (Human) | SUMO-protein ligase,Ubiquitin carrier protein 9,Ubiquitin carrier protein I,Ubiquitin-conjugating enzyme E2 I,Ubiquitin-protein ligase I,p18 |
| 2 | A | 5-chloranyl-3~{H}-1,3-benzoxazole-2-thione | non-polymer | 185.6 | 1 | Chemie (5VM) | |||
| 3 | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A: 2 - 158 (UniProt: P63279)
| PDB | External Database | Details |
|---|---|---|
| Ala 48 | Lys 48 | engineered mutation |
| Ala 49 | Lys 49 | engineered mutation |
| Ala 54 | Glu 54 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17725.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 185.6 | |
| All* | Total formula weight | 17911.0 |
