5F58

Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Retinol-binding protein 2	polymer	133	15570.5	2	UniProt (P50120) Pfam (PF00061)	Homo sapiens (Human)	Cellular retinol-binding protein II,CRBP-II
2	C, F (A, B)	RETINAL	non-polymer		284.4	2	Chemie (RET)
3	D, E, G (A, B)	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
4	H, I (A, B)	water	water		18.0	237	Chemie (HOH)

Sequence modifications

A, B: 1 - 133 (UniProt: P50120)

PDB	External Database	Details
Leu 40	Lys 41	engineered mutation
Val 51	Thr 52	engineered mutation
Phe 58	Arg 59	engineered mutation
Lys 108	Gln 109	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31141.0
Non-Polymers*	Number of molecules	5
	Total formula weight	746.0
All*	Total formula weight	31887.0

*Water molecules are not included.