5F1J

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound 1 at 1.63A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HTH-type transcriptional regulator EthR	polymer	228	25259.3	1	UniProt (P9WMC0) Pfam (PF00440) Pfam (PF21313) UniProt (by SIFTS) (P9WMC1) In PDB	Mycobacterium tuberculosis CDC1551
2	A	3-cyclopentyl-1-pyrrolidin-1-yl-propan-1-one	non-polymer		195.3	2	Chemie (5TO)
3		water	water		18.0	163	Chemie (HOH)

Sequence modifications

A: 2 - 216 (UniProt: P9WMC0)

PDB	External Database	Details
Met -3	-	initiating methionine
Asp -2	-	expression tag
Ile -1	-	expression tag
Glu 0	-	expression tag
Phe 1	-	expression tag
Gly 217	-	expression tag
Ser 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	25259.3
Non-Polymers*	Number of molecules	2
	Total formula weight	390.6
All*	Total formula weight	25649.9

*Water molecules are not included.