5EZN

Crystal Structure of PfCyRPA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cysteine-rich protective antigen	polymer	157	18845.6	1	UniProt (Q8IFM8) Pfam (PF18638) In PDB	Plasmodium falciparum (isolate 3D7)
2	E	Cysteine-rich protective antigen	polymer	176	20649.9	1	UniProt (Q8IFM8) Pfam (PF18638) In PDB	Plasmodium falciparum (isolate 3D7)
3	B	Cysteine-rich protective antigen	polymer	161	19305.0	1	UniProt (Q8IFM8) Pfam (PF18638) In PDB	Plasmodium falciparum
4	G	Cysteine-rich protective antigen	polymer	170	19886.1	1	UniProt (Q8IFM8) Pfam (PF18638) In PDB	Plasmodium falciparum (isolate 3D7)
5		water	water		18.0	5	Chemie (HOH)

Sequence modifications

A: 32 - 185 (UniProt: Q8IFM8)

PDB	External Database	Details
Gln 145	Asn 145	engineered mutation
Lys 186	-	expression tag
Phe 187	-	expression tag
Lys 188	-	expression tag

E: 189 - 362 (UniProt: Q8IFM8)

PDB	External Database	Details
Gln 322	Asn 322	engineered mutation
Gln 338	Asn 338	engineered mutation
Glu 363	-	expression tag
Phe 364	-	expression tag

B: 32 - 198 (UniProt: Q8IFM8)

PDB	External Database	Details
Asp 122	Glu 122	conflict
Gln 145	Asn 145	engineered mutation

G: 193 - 362 (UniProt: Q8IFM8)

PDB	External Database	Details
Gln 338	Asn 338	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	78686.6
All*	Total formula weight	78686.6

*Water molecules are not included.