5EYT

Crystal Structure of Adenylosuccinate Lyase from Schistosoma mansoni in complex with AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adenylosuccinate lyase	polymer	497	56568.4	1	UniProt (G4VQX9) Pfam (PF00206) Pfam (PF10397)	Schistosoma mansoni (Blood fluke)	ASL,Adenylosuccinase
2	B (A)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505)
3	C (A)	water	water		18.0	131	Chemie (HOH)

Sequence modifications

A: 1 - 480 (UniProt: G4VQX9)

PDB	External Database	Details
Met -16	-	initiating methionine
Ala -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Glu -4	-	expression tag
Val -3	-	expression tag
Leu -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	56568.4
Non-Polymers*	Number of molecules	1
	Total formula weight	347.2
All*	Total formula weight	56915.7

*Water molecules are not included.