5EYP
TUBULIN-DARPIN COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tubulin alpha chain | polymer | 451 | 50204.4 | 1 | UniProt (D0VWZ0) Pfam (PF00091) Pfam (PF03953) | Ovis aries (Sheep) | |
| 2 | B (B) | Tubulin beta chain | polymer | 445 | 49999.9 | 1 | UniProt (D0VWY9) Pfam (PF00091) Pfam (PF03953) | Ovis aries (Sheep) | |
| 3 | C (F) | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) | polymer | 169 | 17955.3 | 1 | synthetic construct | ||
| 4 | D (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F, G, M (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | H, I, J, N, O... (A, B, F) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 8 | K (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 9 | L (B) | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | non-polymer | 399.4 | 1 | Chemie (LOC) | |||
| 10 | S, T, U (A, B, F) | water | water | 18.0 | 655 | Chemie (HOH) |
Sequence modifications
A: 1 - 451 (UniProt: D0VWZ0)
B: 1 - 455 (UniProt: D0VWY9)
| PDB | External Database | Details |
|---|---|---|
| Ser 232 | Gly 232 | variant |
| Ser 340 | Thr 340 | variant |
| PDB | External Database | Details |
|---|---|---|
| Cys 203 | Ser 201 | variant |
| Ile 318 | Val 316 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118159.6 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2415.1 | |
| All* | Total formula weight | 120574.7 |
