5EY3

X-ray structure of the thymidine phosphorylase from Salmonella typhimurium in complex with cytidine and sulphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thymidine phosphorylase	polymer	442	47193.8	2	UniProt (Q7CP66) Pfam (PF02885) Pfam (PF00591) Pfam (PF07831)	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	TdRPase
2	C, D, E, F, G... (A, B)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
3	H, N (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL) PubChem (753)
4	I (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	O (B)	4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE	non-polymer		243.2	1	Chemie (CTN) PubChem (16760387) PubChem (24729357) PubChem (25085165) PubChem (54353063) PubChem (44264135) PubChem (58899188) PubChem (44307610) PubChem (44356841) PubChem (45109772) PubChem (596) PubChem (70994952) PubChem (6480064) PubChem (57764456) PubChem (57807005) PubChem (58460874) PubChem (58519508) PubChem (71230474) PubChem (59476533) PubChem (59713247) PubChem (60138999) PubChem (66800112) PubChem (68199635) PubChem (89495334) PubChem (90089493) PubChem (117732781) PubChem (122468509) PubChem (6175) PubChem (6253) PubChem (114682) PubChem (122948) PubChem (160696) PubChem (3013211) PubChem (453552) PubChem (638040) PubChem (1265901) PubChem (5702244) PubChem (6476646) PubChem (6479885) PubChem (6551012) PubChem (6603781) PubChem (6713582) PubChem (12358851) PubChem (142117909) PubChem (148710634) PubChem (168266058) PubChem (171699434)
6	P, Q (A, B)	water	water		18.0	251	Chemie (HOH)

Sequence modifications

A, B: 1 - 440 (UniProt: Q7CP66)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94387.6
Non-Polymers*	Number of molecules	13
	Total formula weight	1354.0
All*	Total formula weight	95741.6

*Water molecules are not included.