5EW2
Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (Human) | Coagulation factor II |
| 2 | B (H) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (Human) | Coagulation factor II |
| 3 | C (D) | HD22 (27mer) | polymer | 27 | 8485.4 | 1 | Homo sapiens | ||
| 4 | D (E) | HD1-deltaT12 | polymer | 15 | 4619.0 | 1 | Homo sapiens | ||
| 5 | E (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | F (H) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | BIRD (PRD_000020) Chemie (0G6) | |||
| 7 | G, H, I (H, D, E) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 8 | J (H) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 46981.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 744.2 | |
| All* | Total formula weight | 47725.3 |
