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5EW1

Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
thrombin light chainpolymer364096.51UniProt (P00734)
Pfam (PF09396)
Homo sapiens (Human)Coagulation factor II
2B
(H)
Thrombin heavy chainpolymer25929780.21UniProt (P00734)
Pfam (PF00089)
Homo sapiens (Human)Coagulation factor II
3C
(D)
HD22 (27mer)polymer278485.41Homo sapiens
4D
(E)
HD1-deltaT3polymer154619.01Homo sapiens
5E
(H)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
6F
(H)
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamidenon-polymer454.01BIRD (PRD_000020)
Chemie (0G6)
7G, H
(D, E)
SODIUM IONnon-polymer23.02Chemie (NA)
8I, J, K, L
(L, H, D, E)
waterwater18.074Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46981.1
Non-Polymers*Number of molecules4
Total formula weight721.2
All*Total formula weight47702.3
*Water molecules are not included.

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PDB entries from 2025-12-10

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