5EW0
Crystal structure of the metallo-beta-lactamase Sfh-I in complex with the bisthiazolidine inhibitor L-CS319
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 234 | 26317.8 | 2 | UniProt (Q9RMI1) Pfam (PF00753) | Serratia fonticola | Metallo-beta-lactamase class B2 Sfh-I |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | (3R,5R,7aS)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid | non-polymer | 237.4 | 2 | Chemie (3C7) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 603 | Chemie (HOH) |
Sequence modifications
A, B: 38 - 269 (UniProt: Q9RMI1)
| PDB | External Database | Details |
|---|---|---|
| Gly 36 | - | expression tag |
| Pro 37 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52635.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 605.5 | |
| All* | Total formula weight | 53241.2 |
