5EVM
Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Fusion glycoprotein F0 | polymer | 529 | 58407.3 | 6 | UniProt (Q9IH63) Pfam (PF00523) In PDB | Nipah virus | Protein F |
| 2 | G | alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G58281NM) | |||
| 3 | H, N, O, U, V | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 4 | I, J, K, R, S... | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G62182OO) | |||
| 5 | L, X | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G21381MC) | |||
| 6 | M | alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G99403XS) | |||
| 7 | P | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G04854NQ) | |||
| 8 | Q, T | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G48068RF) | |||
| 9 | C, D, E, F, A... | MALONATE ION | non-polymer | 102.0 | 6 | Chemie (MLI) |
Sequence modifications
A, B, C, D, E, F: 1 - 531 (UniProt: Q9IH63)
| PDB | External Database | Details |
|---|---|---|
| Asp 67 | Asn 67 | engineered mutation |
| Asp 305 | Asn 305 | engineered mutation |
| Lys 532 | - | expression tag |
| Leu 533 | - | expression tag |
| Met 534 | - | expression tag |
| Lys 535 | - | expression tag |
| Gln 536 | - | expression tag |
| Ile 537 | - | expression tag |
| Glu 538 | - | expression tag |
| Asp 539 | - | expression tag |
| Lys 540 | - | expression tag |
| Ile 541 | - | expression tag |
| Glu 542 | - | expression tag |
| Glu 543 | - | expression tag |
| Ile 544 | - | expression tag |
| Leu 545 | - | expression tag |
| Ser 546 | - | expression tag |
| Lys 547 | - | expression tag |
| Ile 548 | - | expression tag |
| Tyr 549 | - | expression tag |
| His 550 | - | expression tag |
| Ile 551 | - | expression tag |
| Glu 552 | - | expression tag |
| Asn 553 | - | expression tag |
| Glu 554 | - | expression tag |
| Ile 555 | - | expression tag |
| Ala 556 | - | expression tag |
| Arg 557 | - | expression tag |
| Ile 558 | - | expression tag |
| Lys 559 | - | expression tag |
| Lys 560 | - | expression tag |
| Leu 561 | - | expression tag |
| Ile 562 | - | expression tag |
| Gly 563 | - | expression tag |
| Glu 564 | - | expression tag |
| Ala 565 | - | expression tag |
| Pro 566 | - | expression tag |
| Gly 567 | - | expression tag |
| Gly 568 | - | expression tag |
| Ile 569 | - | expression tag |
| Glu 570 | - | expression tag |
| Gly 571 | - | expression tag |
| Arg 572 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 350443.7 | |
| Branched | Number of molecules | 18 |
| Total formula weight | 11530.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 612.3 | |
| All* | Total formula weight | 362586.6 |
