5ETL

E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.82 angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	polymer	162	18312.9	4	UniProt (P26281) Pfam (PF01288) In PDB	Escherichia coli	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase,PPPK,7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase,HPPK
2	A, B, C, D	CALCIUM ION	non-polymer		40.1	11	Chemie (CA)
3	A, B, C, D	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	4	Chemie (ATP)
4	A, B, C, D	2-[(2-azanyl-6-oxidanylidene-3,9-dihydropurin-8-yl)sulfanylmethyl]benzenecarbonitrile	non-polymer		298.3	4	Chemie (5RV)
5		water	water		18.0	528	Chemie (HOH)

Sequence modifications

A, B, C, D: 0 - 158 (UniProt: P26281)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
Ala -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	73251.8
Non-Polymers*	Number of molecules	19
	Total formula weight	3662.9
All*	Total formula weight	76914.6

*Water molecules are not included.