5ETL
E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.82 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | polymer | 162 | 18312.9 | 4 | UniProt (P26281) Pfam (PF01288) | Escherichia coli | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase,PPPK,7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase,HPPK |
| 2 | E, F, G, H, K... (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 11 | Chemie (CA) | |||
| 3 | I, M, R, V (A, B, C, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 4 | J, N, S, W (A, B, C, D) | 2-[(2-azanyl-6-oxidanylidene-3,9-dihydropurin-8-yl)sulfanylmethyl]benzenecarbonitrile | non-polymer | 298.3 | 4 | Chemie (5RV) | |||
| 5 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 528 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 0 - 158 (UniProt: P26281)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ala -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73251.8 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 3662.9 | |
| All* | Total formula weight | 76914.6 |
