5ETH
RORy in complex with inverse agonist 3.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Nuclear receptor ROR-gamma | polymer | 223 | 26012.1 | 2 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | A, B | 1-methyl-~{N}-(1-thiophen-2-ylcarbonyl-3,4-dihydro-2~{H}-quinolin-6-yl)-~{N}-[2,2,2-tris(fluoranyl)ethyl]indole-4-sulfonamide | non-polymer | 533.6 | 2 | Chemie (5RT) | |||
| 3 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A, B: 267 - 487 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 265 | - | expression tag |
| Pro 266 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52024.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1067.2 | |
| All* | Total formula weight | 53091.4 |
