5ESJ
Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G464S mutant complexed with fluconazole
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Lanosterol 14-alpha demethylase | polymer | 539 | 61915.2 | 1 | UniProt (A6ZSR0) Pfam (PF00067) In PDB | Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) | |
2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
3 | A | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL | non-polymer | 306.3 | 1 | Chemie (TPF) | |||
4 | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A: 1 - 530 (UniProt: A6ZSR0)
PDB | External Database | Details |
---|---|---|
Ser 464 | Gly 464 | engineered mutation |
Gly 531 | - | expression tag |
Gly 532 | - | expression tag |
Arg 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
His 537 | - | expression tag |
His 538 | - | expression tag |
His 539 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 61915.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 922.8 | |
All* | Total formula weight | 62838.0 |