5ERP

Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Desmocollin-2	polymer	451	50332.0	2	UniProt (Q02487) Pfam (PF00028)	Homo sapiens (Human)	Cadherin family member 2,Desmocollin-3,Desmosomal glycoprotein II,Desmosomal glycoprotein III
2	C, D, E (C, D, E)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	3	In PDB GlyTouCan (G81315DD)
3	AA, BA, CA, DA, F... (B, A)	alpha-D-mannopyranose	non-polymer		180.2	8	Chemie (MAN)
4	J, K, Z (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	EA, FA, GA, HA, IA... (B, A)	CALCIUM ION	non-polymer		40.1	21	Chemie (CA)
6	PA, V (B, A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
7	QA, RA, W, X, Y (B, A)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
8	SA, TA (A, B)	water	water		18.0	111	Chemie (HOH)

Sequence modifications

A, B: 101 - 545 (UniProt: Q02487)

PDB	External Database	Details
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	100664.0
Branched	Number of molecules	3
	Total formula weight	2246.0
Non-Polymers*	Number of molecules	39
	Total formula weight	3449.0
All*	Total formula weight	106359.0

*Water molecules are not included.