5EQP
Crystal structure of choline kinase alpha-1 bound by 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline (compound 37)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Choline kinase alpha | polymer | 401 | 46856.5 | 2 | UniProt (P35790) Pfam (PF01633) In PDB | Homo sapiens (Human) | CK,CHETK-alpha,Ethanolamine kinase,EK |
2 | A, B | 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline | non-polymer | 255.4 | 2 | Chemie (5R9) | |||
3 | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A, B: 75 - 457 (UniProt: P35790)
PDB | External Database | Details |
---|---|---|
Gly 57 | - | expression tag |
Ser 58 | - | expression tag |
Ser 59 | - | expression tag |
His 60 | - | expression tag |
His 61 | - | expression tag |
His 62 | - | expression tag |
His 63 | - | expression tag |
His 64 | - | expression tag |
His 65 | - | expression tag |
Ser 66 | - | expression tag |
Ser 67 | - | expression tag |
Gly 68 | - | expression tag |
Leu 69 | - | expression tag |
Val 70 | - | expression tag |
Pro 71 | - | expression tag |
Arg 72 | - | expression tag |
Gly 73 | - | expression tag |
Ser 74 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 93713.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 510.7 | |
All* | Total formula weight | 94223.7 |