5EPA

Crystal structure of non-heme alpha ketoglutarate dependent carbocyclase SnoK from nogalamycin biosynthesis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	SnoK	polymer	279	31269.1	6	UniProt (Q9RN60) Pfam (PF05721)	Streptomyces nogalater	carbocyclase SnoK
2	G, I, L, N, R... (A, B, C, D, E...)	FE (III) ION	non-polymer		55.8	6	Chemie (FE)
3	H, J, M, O, S... (A, B, C, D, E...)	2-OXOGLUTARIC ACID	non-polymer		146.1	6	Chemie (AKG)
4	K, P, Q (B, D)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5	AA, V, W, X, Y... (F, A, B, C, D...)	water	water		18.0	999	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 2 - 267 (UniProt: Q9RN60)

PDB	External Database	Details
Met -11	-	initiating methionine
Ala -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Arg -2	-	expression tag
Ser -1	-	expression tag
Ala 0	-	expression tag
Asp 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	187614.4
Non-Polymers*	Number of molecules	15
	Total formula weight	1284.6
All*	Total formula weight	188898.9

*Water molecules are not included.