5ENT
Minocycline bound structure of bacterial efflux pump.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB | polymer | 609 | 65740.7 | 3 | UniProt (P31224) Pfam (PF00873) | Escherichia coli K-12 | AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B,AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B |
| 2 | D, E, F (D, E, F) | DARPin | polymer | 169 | 18317.6 | 3 | synthetic construct | ||
| 3 | G (C) | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE | non-polymer | 457.5 | 1 | Chemie (MIY) | |||
| 4 | H (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
A, B, C: 39 - 329 (UniProt: P31224)
A, B, C: 561 - 869 (UniProt: P31224)
A, B, C: 561 - 869 (UniProt: P31224)
| PDB | External Database | Details |
|---|---|---|
| Gly 552 | - | linker |
| Gly 553 | - | linker |
| Ser 554 | - | linker |
| Gly 555 | - | linker |
| Gly 556 | - | linker |
| Ser 557 | - | linker |
| Gly 558 | - | linker |
| Gly 559 | - | linker |
| Ser 560 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 252174.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 563.6 | |
| All* | Total formula weight | 252738.3 |
