5ENR
MBX3135 bound structure of bacterial efflux pump.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB | polymer | 609 | 65740.7 | 3 | UniProt (P31224) Pfam (PF00873) | Escherichia coli K-12 | AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B,AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B |
| 2 | D, E, F (D, E, F) | DARPin | polymer | 169 | 18317.6 | 3 | synthetic construct | ||
| 3 | G (C) | ~{N}-[4-[2-[[5-cyano-8-[(2~{S},6~{S})-2,6-dimethylmorpholin-4-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridin-6-yl]sulfanyl]ethyl]phenyl]prop-2-enamide | non-polymer | 506.7 | 1 | Chemie (MBX) | |||
| 4 | H, I, J, K, L... (A, B, C, D, E...) | water | water | 18.0 | 801 | Chemie (HOH) |
Sequence modifications
A, B, C: 39 - 329 (UniProt: P31224)
A, B, C: 561 - 869 (UniProt: P31224)
A, B, C: 561 - 869 (UniProt: P31224)
| PDB | External Database | Details |
|---|---|---|
| Gly 552 | - | linker |
| Gly 553 | - | linker |
| Ser 554 | - | linker |
| Gly 555 | - | linker |
| Gly 556 | - | linker |
| Ser 557 | - | linker |
| Gly 558 | - | linker |
| Gly 559 | - | linker |
| Ser 560 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 252174.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 506.7 | |
| All* | Total formula weight | 252681.3 |
