5EJV
RORy in complex with T090131718 and Coactivator peptide EBI96
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Nuclear receptor ROR-gamma | polymer | 262 | 30250.9 | 2 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | B, D (C, D) | EBI96 Coactivator Peptide | polymer | 19 | 2104.4 | 2 | synthetic construct | ||
| 3 | E, F (A, B) | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE | non-polymer | 481.3 | 2 | Chemie (444) | |||
| 4 | G, H, I (A, B, D) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, B: 259 - 518 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 257 | - | expression tag |
| Pro 258 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 64710.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 962.7 | |
| All* | Total formula weight | 65673.2 |
