5EIN
Crystal structure of C148A mutant of LysY from Thermus thermophilus in complex with NADP+ and LysW-gamma-aminoadipic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | N-acetyl-gamma-glutamyl-phosphate/N-acetyl-gamma-aminoadipyl-phosphate reductase | polymer | 344 | 38070.6 | 2 | UniProt (O50146) Pfam (PF01118) Pfam (PF22698) In PDB | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | AGPR,N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase,NAGSA dehydrogenase |
| 2 | C | Alpha-aminoadipate carrier protein LysW | polymer | 54 | 5957.6 | 1 | UniProt (Q9ZND7) Pfam (PF21344) In PDB | Thermus thermophilus | |
| 3 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 4 | B, A | FORMIC ACID | non-polymer | 46.0 | 23 | Chemie (FMT) | |||
| 5 | C | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | water | water | 18.0 | 553 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 344 (UniProt: O50146)
| PDB | External Database | Details |
|---|---|---|
| Ala 148 | Cys 148 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 82098.8 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2610.8 | |
| All* | Total formula weight | 84709.6 |
